Hairy cell leukemia trap
Hairy cell leukemia is an uncommon hematological malignancy characterized by an . The diagnosis can be confirmed by viewing the cells with a special stain known as TRAP (tartrate resistant acid phosphatase). More recently, DB44 testing. APMIS. Mar;(3) The value of tartrate resistant acid phosphatase ( TRAP) immunoreactivity in diagnosis of hairy cell leukemia. Akkaya H(1). The characteristic morphology of the hairy cells; along with correlation with the clinical features, TRAP positivity and immunophenotyping by. Mar 11, · TRAP is found in hairy cell leukemia; other acid phosphatases are found in red blood cells, prostate, white blood cell lysosomes Sensitive and relatively specific for hairy cell carcinoma when combined with DBA positivity (Am J Surg Pathol ;). Hairy cell leukemia is an uncommon hematological malignancy characterized by an accumulation of abnormal B lymphocytes. It is usually classified as a sub-type of chronic lymphocytic leukemia (CLL). Hairy cell leukemia makes up approximately 2% of all leukemias, with fewer than 2, new cases diagnosed annually in North America and Western Europe combined. Hairy cell leukemia (HCL) is a rare neoplasm of mature small B lymphoid cells with characteristic circumferential ‘hairy projections’ involving the peripheral blood, bone marrow and splenic red pulp. With the advent of immunophenotyping and newer treatment modalities, prolonged remission can be Author: Kaumudi Konkay, Megha S. Uppin, Shantveer G. Uppin, D. Raghunadha Rao, Ch. Geetha, T. Roshni Paul.